The treatment of egg recipient and egg donor
Egg donation involves two female participants. The first one is called an egg donor and the second is an egg recipient. The egg donor takes medicines to produce eggs. The eggs are afterwards collected, fertilised in the lab by the sperm of the egg recipient’s husband or partner (or a sperm donor). Eggs are now embryos, and a single one or a pair of them are introduced back into the uterus of the egg recipient to form a pregnancy.
Differences between IVF and IVF with egg donation
The difference between ‘typical IVF’ and ‘egg donation IVF’ is that another person is needed to aid in creating a pregnancy. This lady is the egg donor, whose eggs are used when the potential mother (the egg recipient) cannot use her own eggs to get pregnant. Here we offer you the detailed description of explanation of the egg donation treatment phases.
Synchronising the menstrual cycles
The egg donor and the egg recipient should be at the beginning of their menstrual cycles which is needed to commence egg donation treatment procedures. Even if egg recipient no longer has a regular menstrual cycle, we can have it start in time. This is made by prescribing hormonal medication to both the donor and the egg recipient according to the settled time-table. The medication course is stopped on the same date by both the donor the recipient, starting a ‘withdrawal bleed’ in both women.
The egg donor’s treatment
As soon as the egg donor's period begins, she has an ultrasound examination of the womb and the ovaries to assure the ovaries are inactive and the uterine membrane is thin. Your egg donor then undertakes medication to stimulate her ovaries. After 10 days, she uses one more hormone to make the eggs ready for harvesting. Egg collection is made by aspirating the cells from the follicles by a needle introduced into the ovary through the vagina. After the egg retrieval the donor plays no further role in the egg donation treatment
The egg recipient’s treatment
Egg recipients may or may not have a normal menstrual cycle. This can be regulated and controlled with the help hormonal medication. You may have one or two extra injections of a ‘down-regulating’ drug to make optimal synchronisation with your donor. Once the period is started by the medicine, you will usually have an examination to check that the membrane of your uterus is thin and that there are no cysts in the ovaries right before starting the treatment cycle. This cycle involves taking oestrogen pills, cream or patches to build up your womb membrane again, to ensure you are prepared in the best possible way as a donor egg recipient. Five days before the intended day for Embryo Transfer, you start taking progesterone as well as oestrogen.
Fertilization and embryo transfer
The donor eggs, which were gathered are fertilised with the semen of the male partner or a sperm donor. They are grown in our laboratory for three or (more frequently) five days. During this time, they continue to divide and develop. At five days old, embryos turn into blastocysts. By this part, our expert embryologists can evaluate which embryos have the most promising quality. On the day of embryo transfer, one or two of the excellent quality embryos are moved through the cervical channel into the egg recipient’s uterus using a thin, elastic plastic catheter. This process is usually quick and provides no pain.
Following the embryo transfer, you carry on with taking oestrogen and progesterone containing medication for two weeks and afterwards take a pregnancy test. If the test shows positive result, you should have an examination to verify the pregnancy two weeks later. If a ‘fetal sack’ is seen on the scan, this gives clinical confirmation of your pregnancy.
At O.L.G.A. Fertility Clinic, we achieved 60% pregnancy rates in 2008 after replacing 2 fresh embryos at the 5-day-old blastocyst development stage. The number of children conceived through egg donation is growing each year as more ladies become aware of this sort of treatment.
Interested in egg donation at O.L.G.A. Fertility Clinic?
Please first fill in our questionnaire This will be assessed by one of our experienced doctors, who will then get in touch with you using your preferred contact method.
We look forward to hearing from you!