{"id":10430,"date":"2021-06-09T09:23:14","date_gmt":"2021-06-09T09:23:14","guid":{"rendered":"https:\/\/olgafertilityclinic.com\/?p=10430"},"modified":"2022-09-27T09:29:47","modified_gmt":"2022-09-27T09:29:47","slug":"story-liza-niklas-ivf-pgta","status":"publish","type":"post","link":"https:\/\/olgafertilityclinic.com\/en\/success-stories\/story-liza-niklas-ivf-pgta\/","title":{"rendered":"The Story of Liza and Niklas and their little \u201cGolden Egg\u201d"},"content":{"rendered":"<p>Dear Friends, we are so&nbsp;happy to share with you the story of our dear patients Liza and&nbsp;Niklas who&nbsp;have got their long-awaited daughter Mira at&nbsp;the age of 43 with the help of IVF with their own eggs and&nbsp;PGT-A in&nbsp;O.L.G.A. Clinic.<\/p>\n<div class=\"inset\">\n<p><img decoding=\"async\" class=\"w80p\" src=\"https:\/\/olgafertilityclinic.com\/wp-content\/uploads\/2021\/06\/InstaLive-1.jpg\" alt=\"Watch InstaLive with Lisa and&nbsp;Niklas, where&nbsp;they shared their story, and&nbsp;Dr. Elena, Dr. Irina and&nbsp;Dr. Olga explained our treatment process and&nbsp;answer questions.\" \/><\/p>\n<p><strong>Watch InstaLive with Lisa and&nbsp;Niklas,<\/strong> where&nbsp;they shared their story, and&nbsp;Dr. Elena, Dr. Irina and&nbsp;Dr. Olga explained our treatment process and&nbsp;answered questions.<\/p>\n<p><a class=\"button small\" style=\"background-color: #c22b89;\" href=\"https:\/\/www.instagram.com\/tv\/CQIzYCgnWRl\/?utm_source=ig_web_copy_link\"><strong>Watch Part 1 \u2192<\/strong><\/a><\/p>\n<p><a class=\"button small\" style=\"background-color: #c22b89;\" href=\"https:\/\/www.instagram.com\/tv\/CQI0KCxHclN\/?utm_source=ig_web_copy_link\"><strong>Watch Part 2\u00a0\u2192<\/strong><\/a><\/p>\n<\/div>\n<p><strong>Liza <a href=\"https:\/\/www.instagram.com\/lizabidner\/\">@lizabidner<\/a>\u00a0and Niklas:<\/strong><\/p>\n<blockquote>\n<p><em>We are forever thankful to O.L.G.A. Fertility Clinic; Dr. Elena Lapina and&nbsp;Dr. Irina Uvarova for&nbsp;making our dream come true!<\/em><\/p>\n<p><em>\u2764\ufe0f We have struggled with fertility issues for&nbsp;10 years. We&#8217;ve had one ectopic pregnancy and&nbsp;several miscarriages. We got a miracle after&nbsp;5 years &#8211; a &#8220;surprise&#8221; successful pregnancy while&nbsp;we were waiting to do IVF in&nbsp;Sweden. This pregnancy resulted in&nbsp;our son Linus. Since&nbsp;then, we have tried for&nbsp;a sibling, but&nbsp;nothing happened&#8230; After&nbsp;2 years we got 2 miscarriages in&nbsp;a row. We knew we needed help, but&nbsp;we couldn&#8217;t find it in&nbsp;Sweden. Then we found Dr. Olga Zaytseff!\u2764\ufe0f\u00a0We attended her seminar in&nbsp;Gothenburg in&nbsp;2019, and&nbsp;after that&nbsp;we got consultation with Dr Elena Lapina, who&nbsp;could help us!<\/em><\/p>\n<p><em>We went to St. Petersburg in&nbsp;September 2019 for&nbsp;our egg retrieval (I was 43 at&nbsp;that time), and&nbsp;got 13 eggs, and&nbsp;8 blastocysts. After&nbsp;PGT-A, one &#8220;golden blastocyst&#8221; was found to have a normal number of chromosomes, and&nbsp;7 blastocysts had abnormal numbers of chromosomes.<\/em><\/p>\n<p><em>After&nbsp;one more visit in&nbsp;St Petersburg for&nbsp;a hysteroscopy, we planned to do our embryo transfer in&nbsp;March 2020. Well, the corona-pandemic put an end to our plans. Instead, I went for&nbsp;an embryo transfer in&nbsp;September 2020.<\/em><\/p>\n<p><img decoding=\"async\" class=\"w40p al\" src=\"https:\/\/olgafertilityclinic.com\/wp-content\/uploads\/2021\/06\/184802961_213821616981901_9170421249631953885_n.jpg\" alt=\"The Story of Liza and&nbsp;Niklas\" \/><\/p>\n<p><em>We were lucky, because&nbsp;we succeeded and&nbsp;it resulted in&nbsp;our little princess, Mira! \u2764\ufe0f<\/em><\/p>\n<p><em>14\/5 2021 at&nbsp;13.56, she finally came into the world! Linus&#8217; little sister and&nbsp;our daughter.<\/em><\/p>\n<p><em>Can&#8217;t believe that&nbsp;we succeeded after&nbsp;our first try at&nbsp;IVF with our own eggs! Thank you for&nbsp;your help! You are real miracle-workers!\u00a0After 10 years we are finally a family of four! \u2764\ufe0f\u201d<\/em><\/p>\n<\/blockquote>\n<div class=\"fullw cf\" style=\"background-color: #f7f3ed;\">\n<div class=\"cont\">\n<h2><img decoding=\"async\" class=\"w40p ar\" src=\"https:\/\/olgafertilityclinic.com\/wp-content\/uploads\/2021\/06\/dr-olga-dr-elena.jpg\" alt=\"Dr. Elena and&nbsp;Dr. Olga comment\" \/>Dr. Elena and&nbsp;Dr. Olga comment:<\/h2>\n<h3>I. What was our approach that&nbsp;has helped Liza and&nbsp;Niklas?<\/h3>\n<p>Viable embryos, capable of development up to healthy live birth, have 23 chromosome pairs in&nbsp;their genome. On&nbsp;day 5 it is too early yet, and&nbsp;even&nbsp;if&nbsp;an embryo has reached a blastocyst stage and&nbsp;looks good under the microscope, these good looks do not correlate with normality for&nbsp;23 chromosomes. Hence these good looks do not correlate with the probability of live birth either.<\/p>\n<p>Natural selection in&nbsp;the first 12 weeks of embryonic development still continues, and&nbsp;those embryos with abnormal number of chromosomes, which&nbsp;have achieved implantation, will sadly result in&nbsp;a miscarriage.<\/p>\n<p><strong>Not all that&nbsp;glitters is gold.<br \/>\n<\/strong><\/p>\n<p><strong>Not all the good-looking blastocysts have a normal number of chromosomes.<\/strong><\/p>\n<p> In&nbsp;the age of 43 only one out of 8-9 blastocysts is expected to have a normal number of chromosomes.<\/p>\n<p>Liza happened to be exactly within statistical expectations: 7 out of 8 blastocysts happened to have an abnormal number of chromosomes, and&nbsp;1 out of 8 blastocysts \u2013 normal! Congratulations!<\/p>\n<p>Before&nbsp;transferring this embryo into the uterus, it was important to create the best possible environment for&nbsp;this embryo to stay. We have done hysteroscopy and&nbsp;have found some scar tissue and&nbsp;inflammation in&nbsp;the uterus \u2013 the consequences after&nbsp;Liza\u2019s miscarriages. We have removed scar tissue and&nbsp;treated inflammation, having done everything possible for&nbsp;the \u201cgolden embryo\u201d to wish to implant and&nbsp;stay.<\/p>\n<p>Our efforts were rewarded by successful embryo transfer and&nbsp;healthy live birth! Congratulations!<strong>\u00a0<\/strong><\/p>\n<h3>II. What is\u00a0PGT-A?<\/h3>\n<p>PGT-A is a method which&nbsp;checks embryos for&nbsp;normality for&nbsp;23 chromosomes before&nbsp;a potential transfer. PGT-A helps to exclude abnormal embryos from usage.<\/p>\n<p><strong>By excluding abnormal embryos from usage PGT-A helps:<\/strong><\/p>\n<ul>\n<li>To increase pregnancy rates per embryo transfer<\/li>\n<li>To reduce miscarriage rates per embryo transfer<\/li>\n<li>To increase live birth rates per embryo transfer<\/li>\n<li><strong>To shorten the time to pregnancy (reduces the number of embryo transfers required to create a pregnancy)<\/strong><\/li>\n<\/ul>\n<p>PGT-A is a very helpful method for&nbsp;women above 35 to shorten time to pregnancy.<\/p>\n<p><strong>What proportion of embryos at&nbsp;blastocyst stage are expected to have a normal number of chromosomes?<\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td>35\u201437 years<\/td>\n<td>38\u201440 years<\/td>\n<td>41\u201442 years<\/td>\n<td>43-44 years<\/td>\n<\/tr>\n<tr>\n<td>46%<\/td>\n<td>33%<\/td>\n<td>19%<\/td>\n<td>13%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>For&nbsp;example:<\/strong><\/p>\n<ul>\n<li>Every second blastocyst is expected to have a normal number of chromosomes in&nbsp;the age group 35-37;<\/li>\n<li>In&nbsp;the age of 43 only one out of 8-9\u00a0blastocysts is expected to have a normal number of chromosomes by the age of 43.<\/li>\n<\/ul>\n<p class=\"comment\">[S. Munne et al. Blastocysts needed to transfer at&nbsp;least one euploid embryo: data from 10,852 pre-implantation genetic screening (PGS) cycles. Fertility Sterility September 2015 Volume 104, Issue 3, Supplement, Pages e13\u2013e14]<\/p>\n<h3>III.\u00a0\u00a0We split a big project into three smaller\u00a0projects.<\/h3>\n<p>When&nbsp;a project feels too big and&nbsp;too complex, it is usual to split it into several smaller projects.<\/p>\n<p>So, we do one step at&nbsp;a time.<\/p>\n<p><strong>Every step has its\u2019 goal:<\/strong><\/p>\n<p><strong>Step 1.\u00a0<\/strong>Come to pick up your eggs and&nbsp;get a competent embryo normal for&nbsp;23 chromosomes \u2013 your VIP embryo!<\/p>\n<p><strong>Step 2.\u00a0<\/strong>Come to do hysteroscopy and&nbsp;prepare your uterus \u2013 a luxurious place for&nbsp;your VIP embryo to love it and&nbsp;stay!<\/p>\n<p><strong>Step 3.\u00a0<\/strong>Put your VIP embryo into an optimally prepared and&nbsp;precisely timed environment and&nbsp;support it with reliable hormonal therapy to help it until&nbsp;it is strong enough!<\/p>\n<h3>IV. Reducing the number of transfers till&nbsp;live birth saves our patients from multiple frustrations.<\/h3>\n<p>We believe that&nbsp;women do not exhaust their psychological energy and&nbsp;endurance when&nbsp;coming to St. Petersburg three times. Unlike transfer after&nbsp;transfer, one does not expect to get pregnant when&nbsp;coming to pick up eggs or&nbsp;to do a hysteroscopy.<\/p>\n<p><strong>Only one out of these three trips \u2013 the transfer &#8211; \u00a0is full of expectations but&nbsp;with good reasons:<\/strong><\/p>\n<ul>\n<li>the chromosomally normal competent blastocyst is already created during your visit number 1 and&nbsp;it awaits you in&nbsp;St. Petersburg;<\/li>\n<li>you have already prepared your uterus for&nbsp;successful implantation in&nbsp;your visit number 2.<\/li>\n<\/ul>\n<p>Now&nbsp;you are doing your personalized transfer of a competent chromosomally normal blastocyst in&nbsp;your optimally prepared uterus. And&nbsp;yes, you are full of expectations and&nbsp;hope and&nbsp;with a good reason: by following this technology in&nbsp;O.L.G.A. Clinic you have 50% chance of live birth per one embryo transferred!<\/p>\n<p>We are incredibly grateful to all our amazing Team for&nbsp;making these success rates possible.<\/p>\n<h3>V. Liza and&nbsp;Niklas\u2019s alternative scenarios.\u00a0<\/h3>\n<ol>\n<li>\n<div>How would Liza and&nbsp;Niklas\u2019s\u00a0story have turned out, if&nbsp;embryos had not been genetically tested prior to transfer? &#8211; If&nbsp;no PGT-A had been done,\u00a0<strong>seven\u00a0<\/strong>frustrating embryo transfers of embryos which&nbsp;were predetermined to early pregnancy loss, could have taken several years (together with some miscarriages after)!<\/div>\n<\/li>\n<li>\n<div>Would they have had that&nbsp;much patience to undergo these many transfers experiencing failure after&nbsp;failure?<strong>\u00a0<\/strong>Would Liza have ever come to transfer the golden embryo at&nbsp;all?<\/div>\n<\/li>\n<li>\n<div>What would have happened if&nbsp;Liza and&nbsp;Niklas had had only 7 blastocysts and&nbsp;all of them were abnormal?<br \/>\nThey could have decided for&nbsp;another stimulation and&nbsp;could have found a \u201cgolden embryo\u201d in&nbsp;the following IVF cycle. Or&nbsp;they could have decided to turn to egg donation as&nbsp;another viable way of shortening time to pregnancy.<\/div>\n<\/li>\n<\/ol>\n<p><strong>In&nbsp;our clinic we believe it very important to provide our clients with transparent information about their situation, honest advice and&nbsp;options to choose from. We believe it is very important to have options and&nbsp;guidance.<\/strong><\/p>\n<p><strong><br \/>\nInterested?<\/strong><\/p>\n<ul>\n<li><a href=\"https:\/\/instagram.com\/@dr.olga.zaytseff\"><strong>Join our InstaLive with Liza and&nbsp;Niklas at&nbsp;@dr.olga.zaytseff!<\/strong><\/a> 14 June at&nbsp;19:00 CEST Dr. Elena, Dr. Irina and&nbsp;Dr. Olga explain Liza&#8217;s and&nbsp;Nikla&#8217;s successful process and&nbsp;answer your questions.<\/li>\n<li><a href=\"https:\/\/olgafertilityclinic.com\/en\/events\/\"><strong>Join one of our webinars to find out more<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/olgafertilityclinic.com\/en\/contacts\/how-to-start\/\"><strong>Book yourself a free consultation with one of our fertility specialists<\/strong><\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>We are so happy to share with you the story of our dear patients Liza and Niklas who have got their long-awaited daughter Mira at the age of 43 with the help of IVF with their own eggs and PGT-A in O.L.G.A. Clinic.<\/p>\n","protected":false},"author":1,"featured_media":10477,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[12,11,24,7],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Story of Liza and Niklas and their little \u201cGolden Egg\u201d - O.L.G.A. Fertility<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/olgafertilityclinic.com\/en\/success-stories\/story-liza-niklas-ivf-pgta\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Story of Liza and Niklas and their little \u201cGolden Egg\u201d - O.L.G.A. 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