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1) common term for all the mutation types - deletions, translocations, inversions, duplications; 2) genome mutations - aneuploidies, trisomies | | |
The absence of the menstruation in a woman of reproductive age. Primary amenorrhoea – the initial absence of the menstruation; secondary amenorrhoea – the absence of the menstruation at least for the last six month. | | |
A male sex hormones. | | |
A change in the number of chromosomes, where abnormal numbers of specific chromosomes or chromosome sets exist within the nucleus. | | |
Occurring, existing, or performed before birth, during pregnancy. | | |
Placing sperm into the vagina or uterus. Nowadays, intrauterine insemination is only used. | | |
The opening of the embryo’s covering using, for example, a laser aimed at facilitating implantation of the embryo. | | |
Reduced sperm motility. | | |
A non-sex chromosome. In humans, there are 22 pairs of autosomes. | | |
The medical condition of a man not having any spermatozoa in his semen. Azoospermia has two forms: abstructive azoospermia and non-obstructive azoospermia. | | |
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1) General name of any mutation – deletions, translocations, inversions, duplications. 2) Genomic mutations (aneuploidies, trisomies, etc.). | | |
A threadlike structure in the cell nucleus consisting of DNA and special proteins and providing hereditary materials. Chromosomes contain all or most of the genes of the organism. | | |
From Greek: kryo = cooled, frozen. The cryopreservation is used to preserve the supernumerary embryos, which can then be used for further attempts. Also, spermatozoa can be cryopreserved. | | |
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1) A type of chromosomal aberration in which part of a chromosome is missing. 2) A type of genetic aberration in which a DNA molecule loses its part. | | |
Induced by medicines decrease in endogenous output of hormones. | | |
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A pathological pregnancy, in which implantation has taken place in any tissue other than the uterine wall. | | |
The developing human individual from the time of merging of male and female genetic material in the fertilized egg. Since the 13the week of pregnancy the embryo becomes a fetus. | | |
Placing a dividing fertilized oocyte (embryo) into the uterus with the intent to establish pregnancy. | | |
A frequent cause of the infertility. A common medical condition where the tissue lining the uterus (endometrium) is found outside the uterus causing scar formation. | | |
The abundantly supplied with blood membrane lining the inner surface of the uterus that gets renewed periodically. Embryo implants in endometrium. | | |
From Latin: östrus = readiness to coupling, gen = to cause. Estrogens – female sex hormones produced in the ovaries and controlling the growth of the endometrium. | | |
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Two very fine funnel-shaped tubes that guide spermatozoa to the oocyte and the fertilized oocyte – to the uterus. | | |
The quality or state of being fertile. | | |
The interaction of gametes. | | |
A vesicle in the ovary that contains a developing egg surrounded by a covering of cells. Follicles mature in the ovaries. | | |
Piercing a follicle with a very fine needle to obtain an oocyte. | | |
(follicle stimulating hormone) A hormone produced by the hypophysis and stimulating the growth of immature follicles to maturation. | | |
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Sex cells (ovum and spermatozoon). | | |
A functional unit of inheritance controlling the transmission and expression of one or more traits. A trait can be controlled by several genes. | | |
A term composed of two roots of English and Greek origin: gonos = reproduction, trop = influence on, releasing = setting free. A hormone responsible for release of FSH and LH. | | |
A medicine initially causing increase in FSH and LH secretion, then however it induces a profound hypogonodal effect achieved through downregulation. | | |
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Carriers of information between different organs in the body. | | |
From Latin: chorion = fetal integument, gonad = gonads, trop = to affect. A hormone produced in pregnancy which is medically used to cause ovulation. hCG is extracted from the urine of pregnant females or it is synthesized using biochemical technologies. | | |
From Latin: Menopausa = climax, gonad = sex gland hMG is produced from a sterile preparation of placental glucoprotein urine of post-menopausal women. hMG is used to stimulate ovaries. | | |
The main endocrine gland, controlling functioning of other endocrine glands (gonads, thyroid gland, adrenal gland, etc.); sits in the small, bony cavity at the base of the brain. | | |
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Embedding of the embryo into the endometrium. | | |
From Latin: in vitro = in a test glass, fertilisation = fertilization. IVF means fertilization outside the body. | | |
If a regular sexual life doesn’t result in conceiving a child within a year, physicians call this infertility. However, this state isn’t unchangeable or unrecoverable. | | |
The term is composed of words with roots of Latin origin: intra =in, inside, cytoplasma = content of a cell, spermium = spermatozoon. An in vitro fertilization procedure in which a single sperm is injected directly into an oocyte using a finer microneedle. | | |
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The chromosomal characteristics of a cell; the complete set of chromosomes of a diploid cell; (normal human female karyotype -46, XX; male karyotype - 46, XY); the set of chromosomes specific to this particular organism. | | |
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The time when yellow bodies (corpus luteum) produce progesterone. The lutein phase requires to be supported by administration of exogenous progesterone if there is deficiency in endogenous progesterone. | | |
A hormone that triggers the onset of ovulation. | | |
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A relatively permanent change in hereditary material (DNA, gene, chromosome, genome). | | |
A benign tumor consisting of muscle tissue and normally located in the uterus. Myomas may cause infertility or habitual miscarriage. | | |
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A condition in which spermatogenesis is blocked and no sperm cells are produced . | | |
Because of multiple reasons of miscarriages and IVF failures we split IVF process in parts to solve each of them and achieve live birth
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
How to identify challenges, grow competent eggs, create viable embryos and screen them
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
This webinar about optimizing uterus by hysteroscopy, boosting uterine lining by specific medication, precise timing of embryo transfer with the help of ERA test, hormonal and immune treatment
By Dr. Elena Lapina
Head doctor and co-founder of O.L.G.A. Clinic
How to identify and solve them to achieve successful pregnancy and live birth
By Dr. Elena Lapina
Head doctor and co-founder of O.L.G.A. Clinic
Hot and controversial topics explained from the very beginning — basic genetics, indications, embryo biopsy and freezing, challenges, results and new frontiers
By Dr. Anna Gusareva
Embryo Lab Chief at O.L.G.A. Clinic
How embryos are created and grow in the lab? How embryologists make sure that embryos feel at home in the lab? How to choose the best embryo that will result in live birth?
By Dr. Anna Gusareva
Embryo Lab Chief at O.L.G.A. Clinic
How to make decision and process comfortable and friendly for you, and your result — efficient.
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
Valeria shares different aspects of her work and show even examples of excellent egg donor choices based on physical characteristics and non-physical parameters, such as education, personal motivation, occupation...
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
Egg donation… Embryo adoption…
How normal is the whole process? Who are the donors and what I should/can know about them? Where is the border of my influence?
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
We prepared a very special video where egg donors personally tell about themselves, their principles of life, their reasons to donate and the philosophy of this huge project called "Egg Donation" at O.L.G.A Fertility Clinic
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
By Tatiana Varzaeva
Perinatal psychologist at O.L.G.A. Clinic
