While science and medicine have advanced to tackle many challenges, including infertility, we know that modern methods on their own cannot work without the fine-tuning of our biology. The human body, particularly a woman's reproductive system, requires personalized care and attention to truly make a difference.
The Role of PGT-A
Preimplantation Genetic Testing for Aneuploidies (PGT-A) is a remarkable tool in IVF that identifies chromosomally normal embryos. However, it’s important to understand that PGT-A doesn’t improve the quality of eggs or embryos; it can only select from the ones available. It can check and indicate but never create.
Our Focus: Quality and Quantity of Eggs
To help our patients achieve successful pregnancy using their own eggs we should create as many eggs as possible of as high quality as possible. This will enable us to get enough blastocysts and then PGT-A will identify those that are chromosomally normal.
Did you know that at age 38, only one in three blastocysts is chromosomally normal? This ratio drops to one in five by the age of 41.
Patients who come to us have been through multiple unsuccessful IVFs previously, most of them are over 40 and they usually have a reduced ovarian reserve. The challenge is to get enough blastocysts to find 2-3 chromosomally normal ones. And when we succeed, the chances of a successful pregnancy are high.
Live birth rates per transfer of one chromosomally normal blastocyst are 52%. This means that within three transfers, 9 out of 10 patients achieve a live birth.
Tailored to You: Our Individualized Approach
We don’t just look at numbers; we look at a woman. We analyze her health history and biological characteristics to fine-tune every aspect of her treatment. We improve overall health, influencing immature eggs in ovaries, getting them strong and ready for their final output several months before the actual ovarian stimulation begins.
Then we use individualized stimulation of the ovaries tuned with individual rhythms of each woman’s ovaries, giving eggs enough time to mature, multiply their mitochondria and thus collect energy and strength for the future cell division. The process of eggs’ growth is very personal and delicate, it can be compared to flowers’ blossom as every flower needs its own temperature, level of moisture and blooms at its own speed.
Why Eggs Matter So Much
Think of an egg as the powerhouse of early development.
The egg carries the whole factory for production of the embryo’s cells in the first weeks of development. Sperm just brings a half of genetic material. The egg cytoplasm provides the machine for production, the substrate and the fuel. So, creating competent and viable eggs is the most important part of success. If this is not done, PGT-A is of no use because there will be no blastocysts for testing or there will be weak blastocysts which cannot even be tested.
Thanks to such an individually tailored stimulation, tuned to this particular woman’s biology, 50% of our patients get more blastocysts per one IVF cycle with us than they used to have per one cycle in other clinics before; 33% of our patients are having more blastocysts in one IVF cycle with us than in ALL their IVF cycles previously.
Creating the Perfect Home for Your Embryo
But every single embryo with a normal set of chromosomes needs a nice place to implant, live and grow for 9 months.
So after having got a healthy embryo, we prepare its perfect home.
Many patients of ours have more than one reason why they are not pregnant yet (otherwise they would not have come to us because they would have gotten pregnant at some point at their local clinics). Many have diverse maternal factors interfering with implantation: metabolic, hormonal, immune, inflammation in the uterus and/or the whole body, shifting of implantation window and others.
We will investigate and treat those conditions which may interfere with successful implantation and pregnancy development and only when the environment in the female body and the uterus is fully optimized, we are going to transfer a chromosomally normal embryo into an optimally prepared endometrium in the right timing.
Get in contact
Contact us at info@olgafertilityclinic.com and tell us about your situation and needs. We will analyze your medical data and offer you the most successful strategy and guarantee package. Our consultation is free. The value is priceless.
Take the opportunity to learn more about our approach and ask your questions at our webinars.
Share your story with us, and let us guide you on your unique and shortest possible path to your child.
On the following pages you can read more about:
IVF Math →
For O.L.G.A. Clinic Team an IVF success means a live birth of a baby. Here Dr. Olga Zaytseff, the founder of O.L.G.A. Fertility, provides a detailed explanation of how we determine the number of attempts needed for each individual success, taking into account factors such as age, genetic screening (PGT-A) and egg reserve. Find out more →
IVF Success →
Based on the profound medical expertise, both clinical and scientific, Dr. Elena Lapina, the Medical Director and Co-founder of O.L.G.A. Fertility, emphasizes three main principles for IVF success at O.L.G.A. Fertility. Find out more →
How to defeat failures →
Here we discuss strategies we apply at O.L.G.A. Fertility to enhance IVF success by addressing both embryonic and maternal factors. We explain the importance of genetic testing (PGT-A) to select viable embryos and the role of a well-prepared uterine environment for a successful implantation and further pregnancy development. Find out more →
PGT-A →
PGT-A is one of the key elements of the IVF process at O.L.G.A. Fertility. PGT-A (preimplantation genetic testing for aneuploidies) focuses on screening embryos to identify those with normal chromosome sets and therefore ensures higher pregnancy success rates by reducing miscarriage risks associated with chromosomal abnormalities. Read this page to know more about PGT-A and how it may help you shorten your IVF journey. Find out more →
IVF Process →
Here you can get an overview of a step-by-step IVF process at O.L.G.A. Fertility where each separate step focuses on maximizing the chances for success in achieving pregnancy and live birth. Read this page to get an insight into potential timeframes, possible treatment scenarios and their duration. Find out more →
Because of multiple reasons of miscarriages and IVF failures we split IVF process in parts to solve each of them and achieve live birth
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
How to identify challenges, grow competent eggs, create viable embryos and screen them
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
This webinar about optimizing uterus by hysteroscopy, boosting uterine lining by specific medication, precise timing of embryo transfer with the help of ERA test, hormonal and immune treatment
By Dr. Elena Lapina
Head doctor and co-founder of O.L.G.A. Clinic
How to identify and solve them to achieve successful pregnancy and live birth
By Dr. Elena Lapina
Head doctor and co-founder of O.L.G.A. Clinic
Hot and controversial topics explained from the very beginning — basic genetics, indications, embryo biopsy and freezing, challenges, results and new frontiers
By Dr. Anna Gusareva
Embryo Lab Chief at O.L.G.A. Clinic
How embryos are created and grow in the lab? How embryologists make sure that embryos feel at home in the lab? How to choose the best embryo that will result in live birth?
By Dr. Anna Gusareva
Embryo Lab Chief at O.L.G.A. Clinic
How to make decision and process comfortable and friendly for you, and your result — efficient.
By Dr. Olga Zaytseff
The founder of O.L.G.A. Clinic
Valeria shares different aspects of her work and show even examples of excellent egg donor choices based on physical characteristics and non-physical parameters, such as education, personal motivation, occupation...
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
Egg donation… Embryo adoption…
How normal is the whole process? Who are the donors and what I should/can know about them? Where is the border of my influence?
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
We prepared a very special video where egg donors personally tell about themselves, their principles of life, their reasons to donate and the philosophy of this huge project called "Egg Donation" at O.L.G.A Fertility Clinic
By Valeria Sergeeva
The leading egg donation expert at O.L.G.A. Clinic
By Tatiana Varzaeva
Perinatal psychologist at O.L.G.A. Clinic
